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thiE [2017-07-26 18:48:59]
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thiE [2017-07-26 18:48:59]

thiamine-phosphate pyrophosphorylase
Locus
BSU38290
Isoelectric point
5.06
Molecular weight
23.53 kDa
Protein length
222 aa Sequence Blast
Gene length
666 bp Sequence Blast
Function
biosynthesis of thiamine by 4-methyl-5-(beta-hydroxyethyl)thiazole phosphate to yield thiamine phosphate
Product
thiamine-phosphate pyrophosphorylase
Essential
no
E.C.
2.5.1.3
Synonyms
thiC,ipa-26d,ywbK
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      
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Categories containing this gene/protein

  • Metabolism → Additional metabolic pathways → Biosynthesis of cofactors → Biosynthesis/ acquisition of thiamine

    • Gene

    Coordinates
    3,930,707 → 3,931,375

    The protein

    Catalyzed reaction/ biological activity

  • 2-methyl-4-amino-5-hydroxymethylpyrimidine diphosphate + 4-methyl-5-(2-phosphono-oxyethyl)thiazole = diphosphate + thiamine phosphate (according to Swiss-Prot)

    • Protein family

  • TMP-PPase family (according to Swiss-Prot)

    • Paralogous protein(s)

  • TenI

    • Structure

  • 1G6C PubMed

    • Expression and Regulation

    Operons

    Genes
    ywbI-thiM-thiE
    Description
    PubMed

    Sigma factors

  • SigA: sigma factor, PubMed, in SigA regulon
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    References

    Reviews

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    Original publications

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